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WWOX (WW domain containing oxidoreductase ) Blocking Peptide (the C terminal of WWOX)(100ug)

WWOX (WW domain containing oxidoreductase ) Blocking Peptide (the C terminal of WWOX)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-WWOX Antibody (ARP61394_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAPP47511
Size: 100ug
Weight: 21kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.
Alternative names: D16S432E; FOR; FRA16D; HHCMA56; PRO0128; SDR41C1; WOX1
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