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SERF1A (small EDRK-rich factor 1A (telomeric) ) Blocking Peptide (the N terminal of SERF1A)(100ug)

SERF1A (small EDRK-rich factor 1A (telomeric) ) Blocking Peptide (the N terminal of SERF1A)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-SERF1A Antibody (ARP67287_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP67287
Size: 100ug
Weight: 12kDa
Gene: 8293
Format: Lyophilized powder
Target: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The duplication region includes both a telomeric and a centromeric copy of this gene. Deletions of this gene, the telomeric copy, often accompany deletions of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients, and so it is thought that this gene may be a modifier of the SMA phenotype. The function of this protein is not known; however, it bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product.
Alternative names: 4F5; FAM2A; H4F5; SERF1; SERF1B; SMAM1
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