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Products Monoclonal Anti-HSP70
| Catalogue number: | MA1050 |
| Price: | $200.00 |
| Reactivities: | Human, Rat, Bovine, Rabbit |
| Applications: | Immunohistochemistry, Immunohistochemistry - frozen, Western Blot |
| Size: | 100ug/vial |
| Gene: | Human(3303), Mouse(193740), Rat(24472), Human(3304), Mouse(15511), Rat(294254) |
| Swiss prot: | Human(P08107), Mouse(Q61696), Rat(Q07439), Mouse(P17879) |
| Form: | Lyophilized |
| Format: | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
| Target synonym: | HSPA1; Hsp70-1; Hsp70-2; Heat shock 70 kDa protein 1/2 |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
| Primary protein: | Heat shock 70 kDa protein 1A/1B |
| Scientific background: | Heat-shock proteins, or stress proteins, are expressed in response to heat shock and a variety of other stress stimuli including oxidative free radicals and toxic metal ions. Sargent et al. (1989) identified a duplicated HSP70 locus in the class III region of the major histocompatibility complex on 6p21.3. A duplicated locus encoding the major heat shock-induced protein HSP70 is located in the major histocompatibility complex (MHC) class III region 92 kilobases (kb) telomeric to the C2 gene. The 70-kd mammalian heat shock proteins are structurally and functionally related to the uncoating protein that releases clathrin triskelia from coated vesicles. |
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