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DAND5 (DAN domain family, member 5 ) Blocking Peptide (the C terminal of DAND5)(100ug)

DAND5 (DAN domain family, member 5 ) Blocking Peptide (the C terminal of DAND5)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-DAND5 Antibody (ARP66787_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP66787
Size: 100ug
Weight: 21kDa
Gene: 199699
Format: Lyophilized powder
Target: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
Alternative names: CER2; CERL2; CKTSF1B3; COCO; CRL2; DANTE; GREM3; MGC126849; SP1
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