Reactivities: | Human |
Presku: | AAP67471 |
Size: | 100ug |
Weight: | 38kDa |
Gene: | 90353 |
Format: | Lyophilized powder |
Target: | CTU1 plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). CTU1 directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. |
Alternative names: | ATPBD3; NCS6 |