Reactivities: | Human |
Presku: | AAP68090 |
Size: | 100ug |
Weight: | 13kDa |
Gene: | 25906 |
Format: | Lyophilized powder |
Target: | ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20. |
Alternative names: | APC15; C11orf51 |