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VDR (vitamin D (1,25- dihydroxyvitamin D3) receptor ) Blocking Peptide (the N terminal of VDR)(100ug)

VDR (vitamin D (1,25- dihydroxyvitamin D3) receptor ) Blocking Peptide (the N terminal of VDR)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-VDR Antibody (ARP31243_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAPP31933
Size: 100ug
Weight: 48kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: The nuclear hormone receptor for vitamin D3 also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.
Alternative names: NR1I1
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