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TOP1MT (topoisomerase (DNA) I, mitochondrial ) Blocking Peptide (the C terminal of TOP1MT)(100ug)

TOP1MT (topoisomerase (DNA) I, mitochondrial ) Blocking Peptide (the C terminal of TOP1MT)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-TOP1MT Antibody (ARP66489_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP66489
Size: 100ug
Weight: 70kDa
Gene: 116447
Format: Lyophilized powder
Target: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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