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S-100 (DB 055)

S-100 (DB 055)


Supplier: DB BIOTECH
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S-100
is a low molecular weight protein expressed in glial cells, chondrocytes, macrophages, Langerhans cells, dendritic cells, adipocytes, keratinocytes and breast epithelial cells.

S-100 is involved in regulation of protein phosphorylation, calcium homeostasis, cell differentiation, and inflammatory response.

In clinical diagnostics, S-100 protein expression is used as a marker of certain tumors, melanomas, peripheral nerve sheath tumors, and clear cell sarcomas.