Regulated Upon Activation Normal T cell Express Sequence (RANTES), also called CCL5, is a chemokine produced by T cells three to five days after activation. RANTES is a promiscuous chemokine that signals through several G Protein-coupled receptors, CCR5, CCR3, CCR1 and US28 (a viral receptor encoded by CMV). The main function of RANTES is to recruit immune cells to the site of inflammation. Recombinant RANTES is a non-glycosylated Protein, containing 68 amino acids, with a molecular weight of 7.9 kDa.
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