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MYSM1 (Myb-like, SWIRM and MPN domains 1 ) Blocking Peptide (the N terminal of MYSM1)(100ug)

MYSM1 (Myb-like, SWIRM and MPN domains 1 ) Blocking Peptide (the N terminal of MYSM1)(100ug)


Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-MYSM1 Antibody (ARP67189_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP67189
Size: 100ug
Weight: 91kDa
Gene: 114803
Format: Lyophilized powder
Target: MYSM1 is a metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. It preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. MYSM1 acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
Alternative names: 2A-DUB; 2ADUB; DKFZp779J1554; DKFZp779J1721; KIAA1915; RP4-592A1.1