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GCA Human - Recombinant Human Grancalcin (2ug)

GCA Human - Recombinant Human Grancalcin (2ug)

Supplier: Aviva Systems Biology Incorporated
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Product Introduction: Grancalcin is calcium-binding protein which is particularly abundant in human neutrophils. GCA is a member of the penta EF-hand (PEF) subfamily of EF-hand proteins, who also comprises calpain, sorcin, peflin, and ALG-2. GCA undergoes essential conformational changes upon binding of calcium, which subsequently exposes hydrophobic amino acid residues, that direct the protein to hydrophobic surfaces. GCA cooperates with L-plastin, a protein known to have actin bundling activity, which suggests that GCA has a part in the regulation of neutrophils adhesion.
Product Description: GCA produced in E.Coli is a single, non-glycosylated polypeptide chain containing 237 amino acids (1-217.a.) and having a molecular mass of 26.1kDa. GCA is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Presku: OPPA00162
Size: 2ug
Format: Sterile Filtered clear solution.
Alternative names: Grancalcin EF-hand calcium binding protein; GCL; Grancalcin penta-EF-hand protein.