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ATXN7L3 (ataxin 7-like 3 ) Blocking Peptide (the middle region of ATXN7L3)(100ug)

ATXN7L3 (ataxin 7-like 3 ) Blocking Peptide (the middle region of ATXN7L3)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-ATXN7L3 Antibody (ARP67018_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP67018
Size: 100ug
Weight: 38kDa
Gene: 56970
Format: Lyophilized powder
Target: ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Alternative names: DKFZp761G2113
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